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New Molecular Features of Colorectal Cancer Identified

CPTAC researchers report first large-scale integrated proteomic and genomic analysis of a human cancer.

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For Nature article click here.

Clinical Proteomic Tumor Analysis Consortium

The National Cancer Institute (NCI), part of the National Institutes of Health, announced the launch of a Clinical Proteomic Tumor Analysis Consortium (CPTAC) in August 2011. CPTAC is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of robust, quantitative, proteomic technologies and workflows. Read more.  

Publications

  • Carr SA, Abbatiello SE, Ackermann BL, Borchers C, Domon B, Deutsch EW, Grant RP, Hoofnagle AN, Hüttenhain R, et al. (2014) Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach. Mol Cell Proteomics 13 (3): 907-17. Epub 2014 Jan 17 View PubMed Abstract..
  • Shi T, Sun X, Gao Y, Fillmore TL, Schepmoes AA, Zhao R, He J, Moore RJ, Kagan J, Rodland KD, Liu T, Liu AY, Smith RD, Tang K, Camp DG 2nd, Qian WJ. (2013) Targeted Quantification of Low ng/mL Level Proteins in Human Serum without Immunoaffinity Depletion. J Proteome Res. . Epub ahead of Print View PubMed Abstract.
  • Risk BA, Spitzer WJ, Giddings MC. (2013) Peppy: proteogenomic search software. J Proteome Res. 12 (6): 3019-25. View PubMed abstract.

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