About CPTC
The world of personalized medicine today is very gene-centric. This is not surprising given that genomic studies are among the most promising strategies to help advance personalized medicine efforts. However, while genomics will always remain a cornerstone of personalized medicine, these studies alone cannot capture the complete view of disease processes.
While genes are the "recipes" of the cell, containing all of the instructions for assembly, proteins are the products of these recipes, functioning as the cellular "engines" that drive both normal and disease physiology. So while genomics may provide the likelihood of developing a certain disease, proteins may diagnose what is happening in a patient in real time. Together, these complementary fields (genomics and proteomics) are absolutely necessary for understanding the molecular underpinnings of disease and for enabling personalized medicine.
Recognizing the promise of clinical proteomics for personalized cancer care, the National Cancer Institute (NCI) has taken a lead role in elevating the field by launching the Clinical Proteomic Technologies for Cancer (CPTC) initiative in 2006. This initiative is a highly collaborative effort, made up of scientists from nearly 50 federal, academic, and private-sector organizations, who are working together to make clinical proteomics a reality–far too great an endeavor for a single institution.
CPTC is composed of three major, integrated programs: the Clinical Proteomic Technology Assessment for Cancer (CPTAC) program, the Advanced Platforms and Computational Sciences program, and the Proteomic Reagents and Resources Core.
Click on the links below to learn more about CPTC.
Mission
Visit this page to learn about the mission of CPTC.
Executive Summary
Visit this page to learn more about the challenges that must be overcome before protein biomarkers will be widely available in the clinic – and how CPTC is leading these efforts.
CPTC Leadership
Visit this page to meet the CPTC leadership.
CPTC Community
Visit this page to learn more about the collaborative CPTC community, including the Clinical Proteomic Technology Assessment for Cancer (CPTAC) team network and CPTC partnerships with federal and international agencies as well as small businesses, and to view a list of all organizations participating in the initiative.
Program Milestones
Visit this page to learn about CPTC successes and milestones through an interactive timeline.
Frequently Asked Questions
Visit this page for answers to frequently asked questions about CPTC.
Role of the NCI
Visit this page to learn about other initiatives established by the NCI to help in the fight against cancer.
Related NIH Programs
Visit this page to learn about related NIH initiatives.
Funding Opportunites
Visit this page to learn about specific funding opportunities for the proteomics community.
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