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Omics Integration in Biology and Medicine Workshop

Posted on June 11, 2012

The focus of this meeting will be on the emerging field of integrating disparate omic data from genomics, proteomics, glycomics, etc. in order to better understand key biological processes and also improve clinical practice. Discussants will focus on identifying the technical and biological barriers in omic integration, with solutions to build a consensus towards data integration in bioscience and to better define phenotypes.  As omics science moves forward, identifying methodologies and applications based on specific types of omic data, as well as their integration, becomes increasingly important as it provides new insights to be rapidly tested in basic or applied research.  This meeting sponsored by NHLBI, NCI, and International Forum of Proteomics will be held on June 19 - 20 and can be viewed online at  NIH Videocast, Day 1 and Day 2

Agenda

Day 1, JUNE 19, 2012

08:30 am - 09:00 am Case Study 1:Cancer Specific Example – Omics Study with N of 1

Mike Snyder, Ph.D., Stanford University

09:00 am - 09:30 am Case Study 2: Cardiovascular Specific Example – Personalizing NSAIDS Treatment

John Hogenesch, Ph.D., University of Pennsylvania

10:45 am - 12:00 pm Panel Session: Biology and Medicine: What are the Challenges that Hinder Omics Integration?

Members:
Ivor Benjamin, M.D., University of Utah
Aruni Bhatnagar, Ph.D., University of Louisville
Josef Coresh, M.D., Ph.D., M.H.S., Johns Hopkins University
Joseph Hill, M.D., Ph.D., UT Southwestern Medical Center
Aldons J. Lusis, Ph.D., University of California at Los Angeles
Larry G. Moss, M.D., Duke University
Christopher O’ Donnell, M.D., Framingham Heart Study, NHLBI
Samuel Payne, Ph.D., Pacific Northwest National Laboratory
John Weinstein, M.D., Ph.D., UT MD Anderson Cancer Center

01:30 pm - 02:15 pm Case Study 3:Lessons from the Glycomics Arena

Gerald Hart, Ph.D., Johns Hopkins University
Jennifer Van Eyk, Ph.D., Johns Hopkins University

02:15 pm - 02:45 pm Case Study 4: Application of Omics – Protein Misfolding Diseases and Oxido-Reductive Pathways

Ivor Benjamin, M.D., University of Utah

02:45 pm - 03:30 pm Role of Journals: Recommendations on How to Facilitate the Integration Effort 

Aruni Bhatnagar, Ph.D., Deputy Editor, Circulation Research
Larry G. Moss, M.D., Editorial Board, Journal of Clinical Investigation

04:00 pm - 05:00 pm Panel Session: Technology:  What are the Technological Barriers That Need to be Overcome to Facilitate Omics Integration?

Members:
Scott Geromanos, Waters Corporation
Aldons J. Lusis, Ph.D., University of California at Los Angeles
Ken Miller, Thermo Scientific
Gary Siuzdak, Ph.D., The Scripps Research Institute
John Yates III, Ph.D., The Scripps Research Institute

Day 2, JUNE 20, 2012

08:30 am - 10:00 am Panel Session: Informatics: What Aspects of Informatics Pose the Greatest Challenges to Omics Integration?

Members:
Henning Hermjakob, EMBL, European Bioinformatics Institute
Morgan Giddings, Ph.D., University of North Carolina at Chapel Hill
Peter Munson, Ph.D., CIT, National Institutes of Health
Svati Shah, M.D., M.H.S, Duke University
Nancy Fournier, Ph.D., M.B.A, Genome Québec

10:30 am - 11:15 am Special Presentation: Systems Approach to Biomarker Research in Cardiovascular Disease - The Framingham Heart Study Experience

Daniel Levy, M.D., Framingham Heart Study, NHLBI, Boston University

2:00 pm - 2:30 pm Closing Discussion and Action Items