Emily Boja, Ph.D.

Program Director

Emily Boja

Dr. Boja joined the Office of Clinical Proteomics Cancer Research at the National Cancer Institute in 2009 as a Program Director. She provides scientific expertise and programmatic leadership in managing the Clinial Proteomic Tumor Analysis Consortium (CPTAC) program involving large-scale proteogenomic studies of human cancer specimens and exploring emerging technologies and scientific disciplines to be integrated into the CPTAC portfilio. The overall goals of CPTAC are to improve the understanding of tumor biology, predict drug response to therapy, and reveal the mechanisms of drug resistance. She also oversees the analytical, informatics and regulatory aspects of molecular diagnostics including technologies, platforms and tools in collaboration with the U.S. Food and Drug Administration (FDA) and the American Association of Clinical Chemistry (AACC). For example, understanding regulatory science while applying targeted proteomic assays in the clinic, and led the launch of the first precisionFDA-NCI-CPTAC Multi-Omics Enabled Sample Mislabeling Correction Challenge. Prior to the National Cancer Institute, Dr. Boja served as a Staff Scientist at the Laboratory of Cardiac Energetics where she led the studies on the role of mammalian mitochonrial proteogenomics and phosphoproteomics in OXPHOS and cardiac energetics, following the completion of her postdoctoral Research Fellow training at the Laboratory of Biophysical Chemistry, National Heart, Lung and BIood Institute (intramural programs), NIH. Her expertise originates from her structural biology research on key enzymes and pathways involved in one-carbon metabolism, focusing on the structure-functional relationship and regulation of serine hydroxymethyl transferase on serine synthesis pathways and the impact of its dysregulation on cancer, and later high throughput comprehensive proteomic studies on biological systems. Dr. Boja holds a Ph.D. degree in Biochemistry and Molecular Biology (1999) from the Medical College of Virginia, Virginia Commonwealth University. Dr. Boja co-authored many publications on enzymology, proteomics, and proteogenomics, mentored various undergraduate and graduate level students as a Staff Scientist, and served on an oversight committee of NINDS Proteomics Core Facility, and on many technical evaluation panels for contract proposals.