The Office of Cancer Clinical Proteomics Research (OCCPR) is committed to providing the media with timely and accurate information. This section offers key resources for patients, cancer researchers, physicians, and media professionals.
Dr. Chris Kinsinger, Ph.D., NCI OCCPR, Program Director
Dr. Rajesh Thangudu, Ph.D., Bioinformatic Scientist, ESAC Inc.
Abstract: This webinar will provide a brief overview of NCI’s Proteomic Data Commons (PDC) by Drs. Chris Kinsinger and Ratna Rajesh Thangudu. The speakers show participants how to navigate the website as well as submit data.
Dr. Mehdi Mesri, Ph.D., NCI OCCPR, Program Director
Dr. Karen Ketchum, Ph.D., Director of Strategic Solutions, ESAC Inc.
Dr. Jeffery Whiteaker, Ph.D., Fred Hutchinson Cancer Research Laboratory
Abstract: This webinar that will provide a brief overview of NCI’s Proteomic (CPTAC) Assay Portal by Drs. Mehdi Mesri, Karen Ketchum (ESAC, Inc) and Jeffery Whiteaker (Fred Hutchinson Cancer Research Laboratory). With more than 2,300 proteomic assays available on the Portal, designed and optimized for mass spectroscopy, the speakers talk about the Assay Program, show participants how to navigate the website, as well as discuss assay submission. The speakers also talk about the Clinical Proteomic Tumor Analysis Consortium CPTAC experimental guidelines that ensure that publicly available proteomic assays meet the Consortium’s rigor and reproducibility standards.
Dr. Tara Hiltke, Ph.D., NCI OCCPR, Program Director
Abstract: This webinar that will provide a brief overview of NCI’s Antibody Portal by Dr. Tara Hiltke. Dr. Hiltke talks about the antibody program, shows participants how to navigate the newly re-vamped portal, as well as discusses the "Request For Target" antibody submission requirements through the NCI Antibody Characterization Program.
Dr. Pei Wang of the CPTAC program and Ichan School of Medicine discusses proteogenomics.
Dr. Amanda Paulovich of the CPTAC program and the Fred Hutchinson Cancer Research Center discusses mass spectrometry
Learn about ICPC and how the consortium is breaking down silos to advance proteogenomic cancer research worldwide.
Dr. Henry Rodriguez discusses the future of proteogenomics, precision medicine, and open data in cancer research at the Human Proteome Organization World Congress (HUPO2017).
Dr. Henry Rodriguez gives introduction of keynote speaker, 47th VP of the United States Joseph R. Biden Jr., at the HUPO2017 Global Leadership Gala. View Video.
Keynote speech given by the 47th Vice President of the United States of America Joseph R. Biden Jr. at the HUPO2017 Global Leadership Gala. Inspired by the efforts of the Cancer MoonshotSM initiative, the event raised awareness of HUPO and its activities, advances in proteomics and its impact on human health, and the National Cancer Institute’s (NCI) International Cancer Proteogenome Consortium (ICPC) for pledging to share cancer-related proteogenomic and imaging data hosted by NCI with researchers worldwide. View Video.
Learn about cancer genomics, how it is being integrated with proteomics (termed proteogenomics), and how proteogenomics is anticipated to improve precision medicine. Watch in traditional and simplified Chinese.
Dr. Henry Rodriguez speaks with ecancer television at WIN 2017 about the integration of genomic and proteomic information (proteogenomics) in a patient's tumor into a map for druggable targets. He also highlights aspects of the Cancer MoonshotSM initiative, working with the National Cancer Institute, which aim to open global access to data libraries of tumor genomics and proteomics, including the APOLLO program and the International Cancer Proteogenome Consortium.
Dr. Amanda Paulovich, a member of the Fred Hutch Clinical Research Division, was motivated by an "ethical dilemma" to research how proteins affect the way cancer patients react to cancer drugs. View Video
Dr. Karin Rodland and her colleagues from Pacific Northwest National Laboratory mapped all proteins (proteomics) in ovarian cancer patients, compared them with proteins from normal tissues, and proposed potential therapeutic strategies to better target cancer. Check out the paper at (click here). View Video
PODCAST: Dr. Warren Kibbe & Dr. Henry Rodriguez: Working toward a cure for cancer
October 12, 2016
The Obama administration's cancer moonshot has brought three Federal agencies together - the National Cancer Institute (NCI), the Department of Defense (DoD), and the Department of Veterans Affairs (VA), using state-of-the-art research methods in proteogenomics to more rapidly identify unique targets and pathways of cancer for detection and intervention. Dr. Henry Rodriguez, director of Proteogenomics Research, and Dr. Warren Kibbe, director of the Center for Biomedical Informatics and Information Technology at NCI, join Federal Drive with Tom Temin to discuss what the Institute is bringing to the Applied Proteogenomics OrganizationaL Learning and Outcomes (APOLLO) network.
PODCAST: From Lost in Translation to Paradise Found: Enabling Protein Biomarker Method Transfer by Mass Spectrometry
October 7, 2014
Translation of novel biomarkers into clinical care for the evaluation of therapeutic safety and efficacy has been slow, partly attributable to the cost and complexity of immunoassay development. The potential for liquid chromatography-tandem mass spectrometry (LC-MS/MS) to streamline the translation of novel protein biomarkers is profound. Drs. Henry Rodriguez and Andrew Hoofnagle discuss what the future may be for clinical proteomics. This is an American Association for Clinical Chemistry (AACC) podcast. To listen, click here.
PODCAST: The Journey to Regulation of Protein-Based Multiplex Quantitative Assays
April 22, 2011
Drs. Emily Boja and Henry Rodriguez provide insight into what are the key issues and questions that must be addressed in moving proteomic biological analytes and platforms from research to cleared FDA test. This is an American Association for Clinical Chemistry (AACC) podcast. To listen, click here.
Please check back soon for the 2018 brochures on CPTAC, APOLLO, and ICPC.
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