CPTC and NIST-sponsored Yeast Reference Material Now Publicly Available | Office of Cancer Clinical Proteomics Research

CPTC and NIST-sponsored Yeast Reference Material Now Publicly Available

The yeast protein extract (RM8323) developed by National Institute of Standards and Technology (NIST) under the auspices of NCI's CPTC initiative is currently available to the public at https://www-s.nist.gov/srmors/view_detail.cfm?srm=8323. The yeast proteome offers researchers a unique biological reference material. RM8323 is the most extensively characterized complex biological proteome and the only one associated with several large-scale studies to estimate protein abundance across a wide concentration range. The yeast protein extract and its associated reference datasets (Paulovich et. al., 2009; PMID: 19858499) can be used by the research community for benchmarking instrument detection efficiency for analysis of complex biological proteomes, to improve upon current methods, and to evaluate new platforms when developed.