Omics Integration in Biology and Medicine Workshop

The focus of this meeting will be on the emerging field of integrating disparate omic data from genomics, proteomics, glycomics, etc. in order to better understand key biological processes and also improve clinical practice. Discussants will focus on identifying the technical and biological barriers in omic integration, with solutions to build a consensus towards data integration in bioscience and to better define phenotypes.  As omics science moves forward, identifying methodologies and applications based on specific types of omic data, as well as their integration, becomes increasingly important as it provides new insights to be rapidly tested in basic or applied research.  This meeting sponsored by NHLBI, NCI, and International Forum of Proteomics will be held on June 19 - 20 and can be viewed online at  NIH Videocast, Day 1 and Day 2

Agenda

Day 1, JUNE 19, 2012

08:30 am - 09:00 am Case Study 1:Cancer Specific Example – Omics Study with N of 1

Mike Snyder, Ph.D., Stanford University

09:00 am - 09:30 am Case Study 2: Cardiovascular Specific Example – Personalizing NSAIDS Treatment

John Hogenesch, Ph.D., University of Pennsylvania

10:45 am - 12:00 pm Panel Session: Biology and Medicine: What are the Challenges that Hinder Omics Integration?

Members:
Ivor Benjamin, M.D., University of Utah

Aruni Bhatnagar, Ph.D., University of Louisville

Josef Coresh, M.D., Ph.D., M.H.S., Johns Hopkins University

Joseph Hill, M.D., Ph.D., UT Southwestern Medical Center

Aldons J. Lusis, Ph.D., University of California at Los Angeles

Larry G. Moss, M.D., Duke University

Christopher O’ Donnell, M.D., Framingham Heart Study, NHLBI

Samuel Payne, Ph.D., Pacific Northwest National Laboratory

John Weinstein, M.D., Ph.D., UT MD Anderson Cancer Center

01:30 pm - 02:15 pm Case Study 3:Lessons from the Glycomics Arena

Gerald Hart, Ph.D., Johns Hopkins University

Jennifer Van Eyk, Ph.D., Johns Hopkins University

02:15 pm - 02:45 pm Case Study 4: Application of Omics – Protein Misfolding Diseases and Oxido-Reductive Pathways

Ivor Benjamin, M.D., University of Utah

02:45 pm - 03:30 pm Role of Journals: Recommendations on How to Facilitate the Integration Effort 

Aruni Bhatnagar, Ph.D., Deputy Editor, Circulation Research

Larry G. Moss, M.D., Editorial Board, Journal of Clinical Investigation

04:00 pm - 05:00 pm Panel Session: Technology:  What are the Technological Barriers That Need to be Overcome to Facilitate Omics Integration?

Members:

Scott Geromanos, Waters Corporation

Aldons J. Lusis, Ph.D., University of California at Los Angeles

Ken Miller, Thermo Scientific

Gary Siuzdak, Ph.D., The Scripps Research Institute

John Yates III, Ph.D., The Scripps Research Institute

Day 2, JUNE 20, 2012

08:30 am - 10:00 am Panel Session: Informatics: What Aspects of Informatics Pose the Greatest Challenges to Omics Integration?

Members:

Henning Hermjakob, EMBL, European Bioinformatics Institute

Morgan Giddings, Ph.D., University of North Carolina at Chapel Hill

Peter Munson, Ph.D., CIT, National Institutes of Health

Svati Shah, M.D., M.H.S, Duke University

Nancy Fournier, Ph.D., M.B.A, Genome Québec

10:30 am - 11:15 am Special Presentation: Systems Approach to Biomarker Research in Cardiovascular Disease - The Framingham Heart Study Experience

Daniel Levy, M.D., Framingham Heart Study, NHLBI, Boston University

2:00 pm - 2:30 pm Closing Discussion and Action Items