OCCPR relies on governing body committees to provide objective and expert advice on the coordination and future direction of the CPTAC Program.
The Steering Committee (SC) consists of awardees and OCCPR leadership, who formulate, coordinate, and oversee strategic decisions and policies regarding consortium-wide activities.
The External Scientific Panel (ESP) independently assesses awardee research directions, progress, and strategic plans. The ESP evaluates CPTAC member research and reviews program metrics, while recommending new research opportunities and priorities to the SC to advance CPTAC goals.
The Biospecimen Working Group coordinates tissue sample processing and accrual efforts based on programmatic timelines.
Disease Working Groups are recruited and designated by the CPTAC Steering Committee to identify important biological and clinical questions for a designated cancer type. Questions identified by a DWG serve as a guide on the type of molecular data that should be generated, including analysis of the data produced. DWGs are interdisciplinary and consist of international researchers and physicians.
Data Working Groups ensure that the proteomic data is uploaded to the data coordinating center, determine and coordinate the use of analysis tools for each disease group to analyze data effectively, and incorporate and harmonize the tools into the proteogenomic analytical pipeline.
Program Evaluation provides stewardship of the NCI research investment by overseeing program effectiveness and efficiency and ensuring that programmatic components meet CPTAC goals.