Media

NCI CBIIT Webinar: Proteomic Data Commons in Cancer Research
Wednesday, November 15th, 2023

Speakers:
Dr. Ratna Rajesh Thangudu, Director of Bioinformatics, ICF
Dr. Bing Zhang, Professor of Molecular and Human Genetics, Baylor College of Medicine

This webinar will provide a brief overview of NCI’s Proteomic Data Commons (PDC), which is a secure, cloud-based repository with diverse proteomic data sets and innovative analytic tools. Drs. Thangudu and Zhang will demonstrate the integration of proteomic data from the PDC with various other omics data sets accessible within NCI’s Cancer Research Data Commons and highlight how integrated data can yield new biological and clinical insights.

NCI OCCPR Webinar: Translational Discovery and Validation Using Multi-omics Data from ER+ Breast Tumors
Wednesday, March 17th, 2021

Speaker:
Dr. Meenakshi Anurag, Assistant Professor at Baylor College of Medicine

This webinar will focus on the identification of protein drivers of endocrine therapy resistance in ER+ breast cancer and establishment of the roles of driver and biomarker proteins associated with treatment response.

NCI OCCPR Webinar: Using multi-omics Data to Understand the Cancer Phenotype
Thursday, February 18th, 2021

Speaker:
Dr. Sam Payne, Associate Professor at Brigham Young University

The multiomics perspective has the potential to improve cancer diagnosis and care. This webinar focus on proteogenomic data generated by CPTAC and methods for multiomics data analysis.

NCI OCCPR Webinar: Advances In MS-based Single-cell Proteomics
Tuesday, January 19th, 2021

Speaker:
Dr. Tao Liu, Pacific Northwest National Laboratory

Mass spectrometry-based proteomics enables the characterization of human proteome at a genome scale. Recent advances in sample handling platforms and proteomic analysis strategies also allow for analysis of protein expression and phosphorylation in very small populations of cells, even single cells. These advances in single-cell proteomics holds great potential for improved understanding of biological heterogeneity underlying cancer for translational applications.

NCI OCCPR Webinar: MSFragger
Wednesday, July 15th, 2020

Speaker:
Dr Alexey Nesvizhskii, Professor of Computational Medicine and Bioinformatics & Pathology, University of Michigan

This webinar will demonstrate how to effectively use the ultrafast MSFragger database search tool, developed in 2017, to comprehensively identify peptides.  Dr Nesvizhskii will show how to quickly perform open searches for datasets containing millions of mass spectrometry spectra and analyze large-scale, unbiased detection of post-translational modifications.

NCI OCCPR Webinar: LinkedOmics
Thursday, June 18, 2020

Speaker:
Dr. Eric Jaehnig, Research Associate at Baylor College of Medicine

This webinar will provide a brief overview of the LinkedOmics software developed in the Bing Zhang lab at Baylor University. Dr. Eric Jaehnig shows participants how to use the tool to explore associations between multiple types of omics datasets.

NCI OCCPR Webinar: Network Exploration Tools
Thursday, April 9, 2020

Speakers:
Zeynep Gumus, Ph.D., Assistant Professor, Department of Genetics and Genomics Sciences, Ichan School of Medicine at Mt. Sinai, New York
Selim Kalayci, Ph.D., Postdoctoral Research Fellow, Department of Genetics and Genomics Sciences, Ichan School of Medicine at Mt. Sinai, New York

This webinar will provide a brief overview of the CPTAC Network Exploration Tool ProNetView by Selim Kalayci, Ph.D. in Zeynep Gumus, Ph.D.’s group. The speaker shows participants how to use the three-dimensional tool to explore novel interactions within the context of a specific cancer type.

Principles of Proteomics Series: Bioinformatics
Friday, March 27, 2020

Dr. Bing Zhang of the CPTAC program and Baylor College of Medicine discusses bioinformatics.

Principles of Proteomics Series: Post-translational Modifications
Friday, March 27, 2020

Dr. Steven Carr of the CPTAC program and the Broad Institute of Harvard and MIT discusses post-translational modifications

OCCPR Webinar Series: The Cancer Imaging Archive
Wednesday March 18th, 2020

Speakers:
Mr. Justin Kirby, Technical Director, TCIA

This webinar will provide a brief overview of NCI’s The Cancer Imaging Archive (TCIA)/Clinical Proteomics Tumor Analysis Consortium (CPTAC) imaging database, by Mr. Justin Kirby, Technical Director at TCIA. Mr. Kirby will demonstrate how to navigate the TCIA-CPTAC website for over 6000 images for more than 1500 radiology and histopathology cases associated with the CPTAC proteomic datasets found in the Proteomic Data Commons and its complementary genomic data found at the Genomics Data Commons database.

NCI OCCPR Webinar: Heatmap Visualization Tools
Thursday, February 6, 2020

Speakers:
Anna Calinawan, Biomedical Software Engineer, Ichan School of Medicine at Mt. Sinai, New York

This webinar will provide a brief overview of the CPTAC Heatmap Visualization Tool ProTrack by Anna Calinawan in Pei Wang, Ph.D.’s group, ccrcc.cptac-data-view.org. The speaker shows participants how to explore the tool and query for gene and protein expression.

NCI OCCPR Webinar: NCI Antibody Program
Wednesday, January 22, 2020

Speakers:
Dr. Tara Hiltke, Ph.D., NCI OCCPR, Program Director

This webinar that will provide a brief overview of NCI’s Antibody Portal by Dr. Tara Hiltke. Dr. Hiltke talks about the antibody program, shows participants how to navigate the newly re-vamped portal, as well as discusses the "Request For Target" antibody submission requirements through the NCI Antibody Characterization Program.

Principles of Proteomics Series: Proteogenomics
Friday, December 20, 2019

Dr. Pei Wang of the CPTAC program and Ichan School of Medicine discusses proteogenomics.

Principles of Proteomics Series: Mass Spectrometry
Friday, December 20, 2019

Dr. Amanda Paulovich of the CPTAC program and the Fred Hutchinson Cancer Research Center discusses mass spectrometry

NCI OCCPR Webinar: Proteomic Assay Portal:
Wednesday, December 11, 2019

Speakers:
Dr. Mehdi Mesri, Ph.D., NCI OCCPR, Program Director
Dr. Karen Ketchum, Ph.D., Director of Strategic Solutions, ESAC Inc.
Dr. Jeffery Whiteaker, Ph.D., Fred Hutchinson Cancer Research Laboratory

This webinar that will provide a brief overview of NCI’s Proteomic (CPTAC) Assay Portal by Drs. Mehdi Mesri, Karen Ketchum (ESAC, Inc) and Jeffery Whiteaker (Fred Hutchinson Cancer Research Laboratory). With more than 2,300 proteomic assays available on the Portal, designed and optimized for mass spectroscopy, the speakers talk about the Assay Program, show participants how to navigate the website, as well as discuss assay submission. The speakers also talk about the Clinical Proteomic Tumor Analysis Consortium CPTAC experimental guidelines that ensure that publicly available proteomic assays meet the Consortium’s rigor and reproducibility standards.

NCI OCCPR Webinar: Proteomic Data Commons
Wednesday, November 13, 2019

Speakers:
Dr. Chris Kinsinger, Ph.D., NCI OCCPR, Program Director
Dr. Rajesh Thangudu, Ph.D., Bioinformatic Scientist, ESAC Inc.

This webinar will provide a brief overview of NCI’s Proteomic Data Commons (PDC) by Drs. Chris Kinsinger and Ratna Rajesh Thangudu. The speakers show participants how to navigate the website as well as submit data.

International Cancer Proteogenome Consortium
Wednesday, September 19, 2018

Learn about ICPC and how the consortium is breaking down silos to advance proteogenomic cancer research worldwide.

Perspectives in Proteomics: Interview with Dr. Henry Rodriguez
Friday, May 4, 2018

Dr. Henry Rodriguez discusses the future of proteogenomics, precision medicine, and open data in cancer research at the Human Proteome Organization World Congress (HUPO2017).

Dr. Henry Rodriguez – Introduction of Joe Biden at HUPO2017 Global Leadership Gala
Saturday, September 16, 2017

Dr. Henry Rodriguez gives introduction of keynote speaker, 47th VP of the United States Joseph R. Biden Jr., at the HUPO2017 Global Leadership Gala. View the introduction video.

47th VP of the United States Joseph R. Biden Jr. Speech at HUPO2017 Global Leadership Gala
Saturday, September 16, 2017

Keynote speech given by the 47th Vice President of the United States of America Joseph R. Biden Jr. at the HUPO2017 Global Leadership Gala. Inspired by the efforts of the Cancer Moonshot^SM initiative, the event raised awareness of HUPO and its activities, advances in proteomics and its impact on human health, and the National Cancer Institute’s (NCI) International Cancer Proteogenome Consortium (ICPC) for pledging to share cancer-related proteogenomic and imaging data hosted by NCI with researchers worldwide. View the keynote speech video.

Proteogenomics Research – On the Frontier of Precision Medicine
Thursday, September 14, 2017

Learn about cancer genomics, how it is being integrated with proteomics (termed proteogenomics), and how proteogenomics is anticipated to improve precision medicine. Watch in traditional and simplified Chinese.

Dr. Henry Rodriguez - Proteogenomics in Cancer Medicine
Wednesday, July 5, 2017

Dr. Henry Rodriguez speaks with ecancer television at WIN 2017 about the integration of genomic and proteomic information (proteogenomics) in a patient's tumor into a map for druggable targets. He also highlights aspects of the Cancer Moonshot^SM initiative, working with the National Cancer Institute, which aim to open global access to data libraries of tumor genomics and proteomics, including the APOLLO program and the International Cancer Proteogenome Consortium.

Controlling for variables
Wednesday, May 17, 2017

Dr. Amanda Paulovich, a member of the Fred Hutch Clinical Research Division, was motivated by an "ethical dilemma" to research how proteins affect the way cancer patients react to cancer drugs. View the Controlling for variables video

Mapping Proteins in Cancer/ Cell, June 29, 2016 (Vol. 166, Issue 3)
Wednesday, Jun 29, 2016

Dr. Karin Rodland and her colleagues from Pacific Northwest National Laboratory mapped all proteins (proteomics) in ovarian cancer patients, compared them with proteins from normal tissues, and proposed potential therapeutic strategies to better target cancer. View the "Mapping Proteins in Cancer" paper and video.