Proteomic and phosphoproteomic data for the CPTAC Glioblastoma Discovery Study is now available on the CPTAC Data Portal.
Glioblastoma Multiforme is the most common type of brain cancer in adults with approximately 14,000 new diagnoses each year. Following the molecular profiling of GBM tumors by The Cancer Genome Atlas (TCGA), which identified somatic mutations associated with essential signaling pathways, CPTAC sought to examine both the proteomic and phosphoproteomic profile of GBM tumors.
Using prospectively collected tumor tissue samples from 99 patients and 10 normal brain samples from the Genotype-Tissue Expression (GTEx) program, samples were analyzed to include clinical data (that can be accessed through the CPTAC portal) and imaging data available on The Cancer Imaging Archive (TCIA).
This release includes over 2,057 files and 470 GB of data. Data is free to analyze but is embargoed for publication until March 1, 2021.