Error message

  • Deprecated function: Return type of DateObject::__wakeup() should either be compatible with DateTime::__wakeup(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in include_once() (line 143 of /local/drupal/proteomics/sites/default/modules/date/date_api/date_api.module).
  • Deprecated function: Return type of DateObject::format($format, $force = false) should either be compatible with DateTime::format(string $format): string, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in include_once() (line 143 of /local/drupal/proteomics/sites/default/modules/date/date_api/date_api.module).
  • Deprecated function: Return type of DateObject::setTimezone($tz, $force = false) should either be compatible with DateTime::setTimezone(DateTimeZone $timezone): DateTime, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in include_once() (line 143 of /local/drupal/proteomics/sites/default/modules/date/date_api/date_api.module).
  • Deprecated function: Optional parameter $input declared before required parameter $form_state is implicitly treated as a required parameter in include_once() (line 1439 of /local/drupal/proteomics/includes/bootstrap.inc).
  • Deprecated function: Optional parameter $input declared before required parameter $form_state is implicitly treated as a required parameter in require_once() (line 12 of /local/drupal/proteomics/sites/default/modules/media/media.module).
  • Deprecated function: Optional parameter $module_name declared before required parameter $data is implicitly treated as a required parameter in require_once() (line 18 of /local/drupal/proteomics/sites/default/modules/media/modules/media_wysiwyg/media_wysiwyg.module).
  • Deprecated function: Optional parameter $view_mode declared before required parameter $langcode is implicitly treated as a required parameter in include_once() (line 1439 of /local/drupal/proteomics/includes/bootstrap.inc).
  • Deprecated function: Optional parameter $item declared before required parameter $complete_form is implicitly treated as a required parameter in include_once() (line 1439 of /local/drupal/proteomics/includes/bootstrap.inc).
×

COVID-19 is an emerging, rapidly evolving siituation.

What people with cancer should know: https://www.cancer.gov/coronavirus

Guidance for cancer researchers: https://www.cancer.gov/coronavirus-researchers

Get the latest public health information from CDC: https://www.coronavirus.gov

Get the latest research information from NIH: https://www.nih.gov/coronavirus

Proteomics for the Pediatric Brain Cancer Pilot Study Released on the PDC

The Proteomic Data Commons (PDC) has released data from the Children's Brain Tumor Tissue Consortium (CBTTC): Pediatric Brain Tumor Atlas dataset!

PDC Data Release

The CBTTC and the Pacific Pediatric Neuro-Oncology Consortia (PNOC) are collaborative research consortia focused on identifying therapies for children with brain tumors.  

As a part of their collaboration, they have built the Pediatric Brain Tumor Atlas (PBTA) dataset which houses clinical data for a cohort of almost 1000 pediatric brains tumors, complete with associated whole genome sequencing and RNAseq data. 

To extend the collaboration, CBTTC and CPTAC joined forces to further proteogenomically characterize a subset of these tumors in a pilot study examining seven brain tumor subtypes in children to aid in the identification of therapies for pediatric patients, which is now available on the PDC.

Data included in this release are proteomic and phosphoproteomic analyses of brain tumor samples included in the Kids First PBTA cohort and represent 199 patients analyzed, integrating the proteomic and genomic molecular characterization across seven pediatric and AYA (adolescent and young adult) histologies: Low Grade Glioma, High Grade Glioma, Ependymoma, Ganglioglioma, Craniopharyngioma, Atypical Teratoid Rhabdoid Tumor (ATRT), and Medulloblastoma.

Sample preparation, mass spectroscopy data generation, and data analysis were performed in accordance with CPTAC workflows and the CPTAC Common Data Pipeline.

All raw and processed genomic data, as well as pathology reports, radiology reports, MRIs, histology slide images are hosted by the Gabriella Miller Kids First Data Resource as part of the Gabriella Miller Kids First Pediatric Research Program (Kids First).