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OCCPR: A Leader in Cancer Proteomics and Proteogenomics

The mission of the NCI’s Office of Cancer Clinical Proteomics Research (OCCPR) is to improve prevention, early detection, diagnosis, and treatment of cancer by enhancing the understanding of the molecular mechanisms of cancer, advance proteome and proteogenome science and technology development through community resources (data and reagent), and accelerate the translation of molecular findings into the clinic. This is achieved through OCCPR-supported programs such as the Clinical Proteomic Tumor Analysis Consortium (CPTAC), partnerships with Federal agencies, and collaborations with international organizations/institutions.

The International Cancer Proteogenome Consortium

International Cancer Proteogenome Consortium

Learn about ICPC and how the consortium is breaking down silos to advance proteogenomic cancer research worldwide.

CPTAC Researchers Identify New Features of Ovarian High-Grade Serous Cancer Associated with Patient Survival Rates and Alternative Drug Therapies

In a study published on April 21, in Cell Reports Medicine, researchers with the National Cancer Institutes’ (NCI) Clinical Proteomics Tumor Analysis Consortium (CPTAC) take a comprehensive look at the root causes of ovarian high-grade serous carcinoma (HGSC). Through integrated proteomic and genomic ...


150 New Assays on the NCI Assay Portal!

One of the missions of the Clinical Proteomic Tumor Analysis Consortium (CPTAC) is to provide proteomic resources to the greater scientific community. So, we have great news to announce! CPTAC has added 150 "fit-for-purpose," multiplexed, mass spectrometry-based proteomic targeted assays to its Assay ...


New Quarterly Release of CPTAC Radiology Imaging Data Available

It’s that time again! CPTAC radiology images have been released on the TCIA CPTAC Pathology Portal! Between conference calls and literature searches, take a look at the 38 new radiology and 8 new pathology images added to Portal – all for free!


OCCPR Webinar: Network Exploration Tool for Cancer Research

Finding novel interactions from comprehensive genomics and proteomics (mass spectrometry generated) is made significantly easier with the help of a visual, interactive guide. Researchers from the Mount Sinai Protogenomic Data Analysis Center (PGDAC) team within the Clinical Proteomics Tumor Analysis ...


The Proteomic Data Commons Is Now Live!

NCI announces the launch of the NCI Proteomic Data Commons (PDC)! The PDC is a next-generation proteomics data repository within NCI’s Cancer Research Data Commons with corresponding genomics and imaging data sets to enable data access, analysis, and sharing for integrative research.


New CPTAC Imaging Data Available

New histopathology slides available from CPTAC lung squamous cell carcinoma, lung adenocarcinoma and glioblastoma multiforme studies. 149 images from 28 new cases added in the month of February 2020 are publicly available on the TCIA CPTAC Pathology Portal!


Making Space for Ubiquitin Proteomics

Protein ubiquitylation is best known for its role in degradation, leading molecules to the cell’s recycle bin, but it also has roles in cellular processing and protein interactions. Unfortunately, research using proteomic techniques have been limited due to experimental and technical complications ...


OCCPR Webinar: The Cancer Imaging Archive

The Cancer Imaging Archive (TCIA) houses radiology and histopathology data for the CPTAC Program. There are over 1500 cases and with more than 6000 images…and counting…of 10 cancer types freely available for the public to view. Each case has complementary proteomic data through the Proteomic Data ...


New, Detailed Molecular Roadmap Boosts Fight Against Endometrial Cancer

A study published Feb 13th in Cell provides an unprecedented look at the dozens of molecular steps that occur to bring about endometrial cancer, commonly known as uterine cancer. The study offers insights about how physicians might be able to better identify which patients will need aggressive ...


CPTAC Survey Results Show Success

The Office of Cancer Clinical Proteomics Research (OCCPR) cares what you think about the Clinical Proteomic Tumor Analysis Consortium (CPTAC) program and all its offerings! Working with Clarivate Analytics to conduct a survey, we wanted to determine the effect of the CPTAC program on the ...


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