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The CPTAC Pathology Portal Has New Images

A new batch of CPTAC histopathology imaging data has been released and is now publicly available on the TCIA CPTAC Pathology Portal.

The TCIA quarterly report lists the addition of 76 new pathology slides and 25 new pathology subjects for the cutaneous melanoma, glioblastoma multiforme, and sarcoma tumor types.

TCIA has partnered with CPTAC to host both the radiology and pathology imaging data generated by the CPTAC Program.  Imaging data is available for 10 cancer types including AML, clear cell renal cell carcinoma, head & neck squamous cell carcinoma, lung squamous cell carcinoma, lung adenocarcinoma, ductal carcinoma and corpus endometrial carcinoma.  The TCIA CPTAC Pathology Portal has over 5000 histopathology and radiology slides from almost 1500 proteogenomically analyzed tumor cases.

For help navigating the TCIA CPTAC Pathology Portal, please refer to the TCIA CPTAC Pathology Portal Tutorial.

GDC Releases Harmonized Genomic Data From CPTAC

Data Release-20 from the Genomic Data Commons (GDC) includes genomics from a new CPTAC project!  

The CPTAC Proteogenomic Confirmatory Study examined prospectively collected colon, breast and ovarian tumors for analysis, including harmonized whole exome sequencing, RNA-Seq, and miRNA-Seq that is now available.  Complimentary proteomic and phosphoproteomic analysis can also be found on the CPTAC Data Portal and the Proteomic Data Commons (PDC).

CPTAC has provided the Genomic Data Commons (GDC) with genomic data from over 600 cancer patients with diverse disease types including Lung Adenocarcinoma, Endometrial, Renal, Breast, Colon and Ovarian cancers. The GDC harmonized DNA sequences from CPTAC using GDC DNA-Seq Analysis Pipelines and mRNA Analysis Pipelines.  CPTAC proteomic data are processed through the CPTAC Common Data analysis Pipeline (CDAP).

CPTAC Researchers Reveal Novel Biological Features of Kidney Clear Cell Carcinoma

Investigators with the Kidney Cancer investigations Clinical Proteomic Tumor Analysis Consortium (CPTAC) have generated the most comprehensive multi-omics dataset for clear cell renal cell carcinoma (ccRCC), the most commonly diagnosed kidney cancer subtype. The investigators used integrative proteogenomics, to reveal new insights into kidney cancer.

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